Title

Postprandial Oxidative Stress is Increased After a Phytonutrient-Poor Food But Not After a Kilojoule-Matched Phytonutrient-Rich Food

Document Type

Article

Publication Date

5-2014

Publication Details

This article was originally published as:

Khor, A., Grant, R., Tung, C., Guest, J., Pope, B., ... Bilgin, A. (2014). Postprandial oxidative stress is increased after a phytonutrient-poor food but not after a kilojoule-matched phytonutrient -rich food. Nutrition Research, 34(5), 391-400. doi: 10.1016/j.nutres.2014.04.005

ISSN: 0271-5317

ANZSRC / FoR Code

111199 Nutrition and Dietetics not elsewhere classified

Abstract

Research indicates that energy-dense foods increase inflammation and oxidative activity, thereby contributing to the development of vascular disease. However, it is not clear whether the high kilojoule load alone, irrespective of the nutritional content of the ingested food, produces the postprandial oxidative and inflammatory activity. This study investigated the hypothesis that ingestion of a high-fat, high-sugar, phytonutrient-reduced food (ice cream) would increase oxidative and inflammatory activity greater than a kilojoule-equivalent meal of a phytonutrient-rich whole food (avocado).

The individual contributions of the fat/protein and sugar components of the ice cream meal to postprandial inflammation and oxidative stress were also quantified. Using a randomized, crossover design, 11 healthy participants ingested 4 test meals: ice cream, avocado, the fat/protein component in ice cream, and the sugar equivalent component in ice cream. Plasma glucose, cholesterol, triglycerides, and inflammatory and oxidative stress markers were measured at baseline and 1, 2, and 4 hours (t1, t2, t4) after ingestion. Lipid peroxidation was increased at 2 hours after eating fat/protein (t0-t2, P < .05) and sugar (t1-t2, P < .05; t1-t4, P < .05). Antioxidant capacity was decreased at 4 hours after eating ice cream (t0-t4, P < .01) and sugar (t0-t4, P < .01).

Ingestion of a kilojoule-equivalent avocado meal did not produce any changes in either inflammatory or oxidative stress markers. These data indicate that the ingestion of a phytonutrient-poor food and its individual fat/protein or sugar components increase plasma oxidative activity. This is not observed after ingestion of a kilojoule-equivalent phytonutrient-rich food.

Comments

Due to copyright restrictions this article is unavailable for download.

This article may be accessed from the publisher here.

Staff and Students of Avondale College may access the full text of this article from library PRIMO search.

Please refer to publisher version or contact the library.

Share

COinS