Author Faculty (Discipline)

Nursing

Document Type

Article

Publication Date

6-15-2020

Early Online Version

7-30-2019

JOURNAL

Clinical Infectious Diseases

VOLUME NUMBER

70

ISSUE NUMBER

12

PAGE NUMBERS

2461-2468

ISSN

1537-6591

Embargo Period

11-5-2019

ANZSRC / FoR Code

060502 Infectious Agents| 111001 Aged Care Nursing| 111003 Clinical Nursing: Secondary (Acute Care)| 111716 Preventive Medicine

Avondale Research Centre

Lifestyle and Health Research Centre

Reportable Items (HERDC/ERA)

C1

Abstract

Background

Healthcare-associated infections (HAIs) remain a significant patient safety issue, with point prevalence estimates being ~5% in high-income countries. In 2016–2017, the Researching Effective Approaches to Cleaning in Hospitals (REACH) study implemented an environmental cleaning bundle targeting communication, staff training, improved cleaning technique, product use, and audit of frequent touch-point cleaning. This study evaluates the cost-effectiveness of the environmental cleaning bundle for reducing the incidence of HAIs.

Methods

A stepped-wedge, cluster-randomized trial was conducted in 11 hospitals recruited from 6 Australian states and territories. Bundle effectiveness was measured by the numbers of Staphylococcus aureus bacteremia, Clostridium difficile infection, and vancomycin-resistant enterococci infections prevented in the intervention phase based on estimated reductions in the relative risk of infection. Changes to costs were defined as the cost of implementing the bundle minus cost savings from fewer infections. Health benefits gained from fewer infections were measured in quality-adjusted life-years (QALYs). Cost-effectiveness was evaluated using the incremental cost-effectiveness ratio and net monetary benefit of adopting the cleaning bundle over existing hospital cleaning practices.

Results

Implementing the cleaning bundle cost $349 000 Australian dollars (AUD) and generated AUD$147 500 in cost savings. Infections prevented under the cleaning bundle returned a net monetary benefit of AUD$1.02 million and an incremental cost-effectiveness ratio of $4684 per QALY gained. There was an 86% chance that the bundle was cost-effective compared with existing hospital cleaning practices.

Conclusions

A bundled, evidence-based approach to improving hospital cleaning is a cost-effective intervention for reducing the incidence of HAIs.

Link to publisher version (DOI)

https://doi.org/10.1093/cid/ciz717

Peer Review

Before publication

Grant Number

GNT1076006

Grant Link

http://purl.org/au-research/grants/nhmrc/GNT1076006

Comments

Used by permission: the author(s).


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