Increasing Incidence of Clostridium difficile Infection, Australia, 2011-2012

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avondale-bepress-to-dspace.facultyNursing
avondale-bepress-to-dspace.peer_review_statusPeer reviewed before publication
avondale-bepress.abstract<p>Objectives: To report the quarterly incidence of hospital-identified <em>Clostridium difficile </em>infection (HI-CDI) in Australia, and to estimate the burden ascribed to hospital-associated (HA) and community-associated (CA) infections.</p> <p>Design, setting and patients: Prospective surveillance of all cases of CDI diagnosed in hospital patients from 1 January 2011 to 31 December 2012 in 450 public hospitals in all Australian states and the Australian Capital Territory. All patients admitted to inpatient wards or units in acute public hospitals, including psychiatry, rehabilitation and aged care, were included, as well as those attending emergency departments and outpatient clinics.</p> <p>Main outcome measures: Incidence of HI-CDI (primary outcome); proportion and incidence of HA-CDI and CA-CDI (secondary outcomes).</p> <p>Results: The annual incidence of HI-CDI increased from 3.25/10 000 patient days (PD) in 2011 to 4.03/10 000 PD in 2012. Poisson regression modelling demonstrated a 29% increase (95% CI, 25% to 34%) per quarter between April and December 2011, with a peak of 4.49/10 000 PD in the October–December quarter. The incidence plateaued in January–March 2012 and then declined by 8% (95% CI, 11% to 5%) per quarter to 3.76/10 000 PD in July–September 2012, after which the rate rose again by 11% (95% CI, 4% to 19%) per quarter to 4.09/10 000 PD in October–December 2012. Trends were similar for HA-CDI and CA-CDI. A subgroup analysis determined that 26% of cases were CA-CDI.</p> <p>Conclusions: A significant increase in both HA-CDI and CA-CDI identified through hospital surveillance occurred in Australia during 2011–2012. Studies are required to further characterise the epidemiology of CDI in Australia.</p>
avondale-bepress.articleid1054
avondale-bepress.authorsClaudia Slimings
avondale-bepress.authorsPaul Armstrong
avondale-bepress.authorsWendy Beckingham
avondale-bepress.authorsAnn Bull
avondale-bepress.authorsLisa Hall
avondale-bepress.authorsKarina Kennedy
avondale-bepress.authorsJohn Marquess
avondale-bepress.authorsRebecca McCann
avondale-bepress.authorsAndrea Menzies
avondale-bepress.authorsBrett G Mitchell
avondale-bepress.authorsMichael Richards
avondale-bepress.authorsPaul Smollen
avondale-bepress.authorsLauren Tracey
avondale-bepress.authorsIrene Wilkinson
avondale-bepress.authorsFiona Wilson
avondale-bepress.authorsLeon Worth
avondale-bepress.authorsThomas V Riley
avondale-bepress.context-key5424380
avondale-bepress.coverpage-urlhttps://research.avondale.edu.au/nh_papers/53
avondale-bepress.document-typearticle
avondale-bepress.field.author_faculty_disciplineNursing
avondale-bepress.field.comments<p>Due to copyright restrictions this article is unavailable for download.</p> <p>The full text of this article can be accessed from <a href="https://www.mja.com.au/journal/2014/200/5/increasing-incidence-clostridium-difficile-infection-australia-2011-2012">The Medical Journal of Australia.</a></p>
avondale-bepress.field.custom_citation<p>Slimings, C., Armstrong, P., Beckingham, W., Bull, A., Hall, L., ...Riley, T. (2014). Increasing incidence of clostridium difficile infection, Australia, 2011-2012. <em>Medical Journal of Australia, 200</em>(5), 272-276.</p>
avondale-bepress.field.doihttps://doi.org/10.5694/mja13.11153
avondale-bepress.field.embargo_date2014-04-01T00:00:00Z
avondale-bepress.field.field_of_education06 Health
avondale-bepress.field.for060502 Infectious Agents
avondale-bepress.field.issn1326-5377
avondale-bepress.field.issue_number5
avondale-bepress.field.journalMedical Journal of Australia
avondale-bepress.field.page_numbers272-276
avondale-bepress.field.peer_reviewBefore publication
avondale-bepress.field.publication_date2014-03-17T00:00:00Z
avondale-bepress.field.reportable_itemsC1
avondale-bepress.field.research_centreLifestyle Research Centre
avondale-bepress.field.source_fulltext_urlhttps://www.mja.com.au/journal/2014/200/5/increasing-incidence-clostridium-difficile-infection-australia-2011-2012
avondale-bepress.field.source_publication<p>This article was originally published as:</p> <p>Slimings, C., Armstrong, P., Beckingham, W., Bull, A., Hall, L., ...Riley, T. (2014). Increasing incidence of clostridium difficile infection, Australia, 2011-2012. <em>Medical Journal of Australia, 200</em>(5), 272-276.</p> <p>ISSN: 1326-5377</p> <p>DOI:10.5694/mja13.11153</p>
avondale-bepress.field.staff_classificationPermanent
avondale-bepress.field.volume_number200
avondale-bepress.keywordsclostridium difficile
avondale-bepress.keywordssurveillance
avondale-bepress.keywordshealthcare
avondale-bepress.keywordsinfection
avondale-bepress.label53
avondale-bepress.publication-date2014-03-17T00:00:00Z
avondale-bepress.publication-titleNursing and Health Papers and Journal Articles
avondale-bepress.statepublished
avondale-bepress.submission-date2014-04-01T19:55:10Z
avondale-bepress.submission-pathnh_papers/53
avondale-bepress.titleIncreasing Incidence of Clostridium difficile Infection, Australia, 2011-2012
avondale-bepress.typearticle
dc.contributor.authorRiley, Thomas V.
dc.contributor.authorWorth, Leon
dc.contributor.authorWilson, Fiona
dc.contributor.authorWilkinson, Irene
dc.contributor.authorTracey, Lauren
dc.contributor.authorSmollen, Paul
dc.contributor.authorRichards, Michael
dc.contributor.authorMitchell, Brett G.
dc.contributor.authorMenzies, Andrea
dc.contributor.authorMcCann, Rebecca
dc.contributor.authorMarquess, John
dc.contributor.authorKennedy, Karina
dc.contributor.authorHall, Lisa
dc.contributor.authorBull, Ann
dc.contributor.authorBeckingham, Wendy
dc.contributor.authorArmstrong, Paul
dc.contributor.authorSlimings, Claudia
dc.date.accessioned2023-11-01T00:37:45Z
dc.date.available2023-11-01T00:37:45Z
dc.date.issued2014-03-17
dc.date.submitted2014-04-01T19:55:10Z
dc.description.abstract<p>Objectives: To report the quarterly incidence of hospital-identified <em>Clostridium difficile </em>infection (HI-CDI) in Australia, and to estimate the burden ascribed to hospital-associated (HA) and community-associated (CA) infections.</p> <p>Design, setting and patients: Prospective surveillance of all cases of CDI diagnosed in hospital patients from 1 January 2011 to 31 December 2012 in 450 public hospitals in all Australian states and the Australian Capital Territory. All patients admitted to inpatient wards or units in acute public hospitals, including psychiatry, rehabilitation and aged care, were included, as well as those attending emergency departments and outpatient clinics.</p> <p>Main outcome measures: Incidence of HI-CDI (primary outcome); proportion and incidence of HA-CDI and CA-CDI (secondary outcomes).</p> <p>Results: The annual incidence of HI-CDI increased from 3.25/10 000 patient days (PD) in 2011 to 4.03/10 000 PD in 2012. Poisson regression modelling demonstrated a 29% increase (95% CI, 25% to 34%) per quarter between April and December 2011, with a peak of 4.49/10 000 PD in the October–December quarter. The incidence plateaued in January–March 2012 and then declined by 8% (95% CI, 11% to 5%) per quarter to 3.76/10 000 PD in July–September 2012, after which the rate rose again by 11% (95% CI, 4% to 19%) per quarter to 4.09/10 000 PD in October–December 2012. Trends were similar for HA-CDI and CA-CDI. A subgroup analysis determined that 26% of cases were CA-CDI.</p> <p>Conclusions: A significant increase in both HA-CDI and CA-CDI identified through hospital surveillance occurred in Australia during 2011–2012. Studies are required to further characterise the epidemiology of CDI in Australia.</p>
dc.description.versionBefore publication
dc.identifier.citation<p>Slimings, C., Armstrong, P., Beckingham, W., Bull, A., Hall, L., ...Riley, T. (2014). Increasing incidence of clostridium difficile infection, Australia, 2011-2012. <em>Medical Journal of Australia, 200</em>(5), 272-276.</p>
dc.identifier.doihttps://doi.org/10.5694/mja13.11153
dc.identifier.issn1326-5377
dc.identifier.urihttps://research.avondale.edu.au/handle/123456789/05424380
dc.language.isoen_us
dc.provenance<p>This article was originally published as:</p> <p>Slimings, C., Armstrong, P., Beckingham, W., Bull, A., Hall, L., ...Riley, T. (2014). Increasing incidence of clostridium difficile infection, Australia, 2011-2012. <em>Medical Journal of Australia, 200</em>(5), 272-276.</p> <p>ISSN: 1326-5377</p> <p>DOI:10.5694/mja13.11153</p>
dc.rights<p>Due to copyright restrictions this article is unavailable for download.</p> <p>The full text of this article can be accessed from <a href="https://www.mja.com.au/journal/2014/200/5/increasing-incidence-clostridium-difficile-infection-australia-2011-2012">The Medical Journal of Australia.</a></p>
dc.subjectclostridium difficile
dc.subjectsurveillance
dc.subjecthealthcare
dc.subjectinfection
dc.titleIncreasing Incidence of Clostridium difficile Infection, Australia, 2011-2012
dc.typeJournal Article
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