A Randomised Controlled Trial Investigating the Effect of Improving the Cleaning and Disinfection of Shared Medical Equipment on Healthcare-associated Infections: The CLEaning and Enhanced disiNfection (CLEEN) Study

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avondale-bepress-to-dspace.facultyNursing
avondale-bepress-to-dspace.grantGNT2008392
avondale-bepress-to-dspace.licensehttp://creativecommons.org/licenses/by/4.0/
avondale-bepress-to-dspace.peer_review_statusPeer reviewed before publication
avondale-bepress.abstract<p><h3>Background</h3></p> <p>Healthcare-associated infections (HAIs) are a common, costly, yet largely preventable complication impacting patients in healthcare settings globally. Improving routine cleaning and disinfection of the hospital environment has been shown to reduce the risk of HAI. Contaminated shared medical equipment presents a primary transmission route for infectious pathogens, yet is rarely studied. The CLEEN study will assess how enhanced cleaning and disinfection of shared medical equipment affects the rate of HAIs in a tertiary hospital setting. The initiative is an evidence-based approach combining staff training, auditing and feedback to environmental services staff to enhance cleaning and disinfection practices. <h3>Methods</h3></p> <p>The CLEEN study will use a stepped wedge randomised controlled design in 10 wards of one large Australian hospital over 36 weeks. The intervention will consist of 3 additional hours per weekday for the dedicated cleaning and disinfection of shared medical equipment on each ward. The primary outcome is to demonstrate the effectiveness of improving the quality and frequency of cleaning shared medical equipment in reducing HAIs, as measured by a HAI point prevalence study (PPS). The secondary outcomes include the thoroughness of equipment cleaning assessed using fluorescent marker technology and the cost-effectiveness of the intervention. <h3>Discussion</h3></p> <p>Evidence from the CLEEN study will contribute to future policy and practice guidelines about the cleaning and disinfection of shared medical equipment. It will be used by healthcare leaders and clinicians to inform decision-making and implementation of best-practice infection prevention strategies to reduce HAIs in healthcare facilities. <h3>Trial registration</h3></p> <p>Australia New Zealand Clinical Trial Registry ACTRN12622001143718.</p>
avondale-bepress.articleid1269
avondale-bepress.authorsKatrina Browne
avondale-bepress.authorsNicole White
avondale-bepress.authorsPeta Tehan
avondale-bepress.authorsPhilip Russo
avondale-bepress.authorsMaham Amin
avondale-bepress.authorsAndrew Stewardson
avondale-bepress.authorsAllen Cheng
avondale-bepress.authorsKirsty Graham
avondale-bepress.authorsGabrielle O'Kane
avondale-bepress.authorsJennie King
avondale-bepress.authorsMartin Kiernan
avondale-bepress.authorsDavid Brain
avondale-bepress.authorsBrett Mitchell
avondale-bepress.context-key34688453
avondale-bepress.coverpage-urlhttps://research.avondale.edu.au/nh_papers/261
avondale-bepress.document-typearticle
avondale-bepress.field.accepted_versionPublished Version
avondale-bepress.field.author_faculty_disciplineNursing
avondale-bepress.field.comments<p>Used by permission: the author(s).</p>
avondale-bepress.field.custom_citation<p>Browne, K., White, N., Tehan, P., Russo, P. L., Amin, M., Stewardson, A. J., Cheng, A. C., Graham, K., O'Kane, G., King, J., Kiernan, M., Brain, D., & Mitchell, B. G. (2023)<em>.</em> A randomised controlled trial investigating the effect of improving the cleaning and disinfection of shared medical equipment on healthcare-associated infections: the CLEaning and Enhanced disiNfection (CLEEN) study. <em>Trials, 24</em>(1), Article 133. https://doi.org/10.1186/s13063-023-07144-z</p>
avondale-bepress.field.distribution_licensehttp://creativecommons.org/licenses/by/4.0/
avondale-bepress.field.doihttps://doi.org/10.1186/s13063-023-07144-z
avondale-bepress.field.embargo_date2023-04-02T00:00:00Z
avondale-bepress.field.field_of_education06 Health
avondale-bepress.field.for_20213107 Microbiology
avondale-bepress.field.grant_numGNT2008392
avondale-bepress.field.grant_purl<p><a href="https://www.nhmrc.gov.au/sites/default/files/documents/attachments/NHMRC%20Grant%20Data%202022.xlsx" target="_blank">https://www.nhmrc.gov.au/sites/default/files/documents/attachments/NHMRC%20Grant%20Data%202022.xlsx</a></p> <p><a href="https://cleenstudy.com/">https://cleenstudy.com/</a></p>
avondale-bepress.field.issn1745-6215
avondale-bepress.field.issue_number1
avondale-bepress.field.journalTrials
avondale-bepress.field.page_numbers133
avondale-bepress.field.peer_reviewBefore publication
avondale-bepress.field.publication_date2023-02-22T00:00:00Z
avondale-bepress.field.reportable_itemsC1
avondale-bepress.field.research_centreLifestyle Medicine and Health Research Centre
avondale-bepress.field.source_fulltext_urlhttps://trialsjournal.biomedcentral.com/articles/10.1186/s13063-023-07144-z#citeas
avondale-bepress.field.staff_classificationContract
avondale-bepress.field.volume_number24
avondale-bepress.fulltext-urlhttps://research.avondale.edu.au/cgi/viewcontent.cgi?article=1269&amp;context=nh_papers&amp;unstamped=1
avondale-bepress.keywordsHospitals Cleaning Cross-infection Cost-effectiveness Shared medical equipment Infection control Health services Disinfection
avondale-bepress.label261
avondale-bepress.publication-date2023-02-22T00:00:00Z
avondale-bepress.publication-titleNursing and Health Papers and Journal Articles
avondale-bepress.statepublished
avondale-bepress.submission-date2023-04-02T16:20:15Z
avondale-bepress.submission-pathnh_papers/261
avondale-bepress.titleA Randomised Controlled Trial Investigating the Effect of Improving the Cleaning and Disinfection of Shared Medical Equipment on Healthcare-associated Infections: The CLEaning and Enhanced disiNfection (CLEEN) Study
avondale-bepress.typearticle
dc.contributor.authorMitchell, Brett
dc.contributor.authorBrain, David
dc.contributor.authorKiernan, Martin
dc.contributor.authorKing, Jennie
dc.contributor.authorO'Kane, Gabrielle
dc.contributor.authorGraham, Kirsty
dc.contributor.authorCheng, Allen
dc.contributor.authorStewardson, Andrew
dc.contributor.authorAmin, Maham
dc.contributor.authorRusso, Philip
dc.contributor.authorTehan, Peta
dc.contributor.authorWhite, Nicole
dc.contributor.authorBrowne, Katrina
dc.date.accessioned2023-11-01T00:35:58Z
dc.date.available2023-11-01T00:35:58Z
dc.date.issued2023-02-22
dc.date.submitted2023-04-02T16:20:15Z
dc.description.abstract<p><h3>Background</h3></p> <p>Healthcare-associated infections (HAIs) are a common, costly, yet largely preventable complication impacting patients in healthcare settings globally. Improving routine cleaning and disinfection of the hospital environment has been shown to reduce the risk of HAI. Contaminated shared medical equipment presents a primary transmission route for infectious pathogens, yet is rarely studied. The CLEEN study will assess how enhanced cleaning and disinfection of shared medical equipment affects the rate of HAIs in a tertiary hospital setting. The initiative is an evidence-based approach combining staff training, auditing and feedback to environmental services staff to enhance cleaning and disinfection practices. <h3>Methods</h3></p> <p>The CLEEN study will use a stepped wedge randomised controlled design in 10 wards of one large Australian hospital over 36 weeks. The intervention will consist of 3 additional hours per weekday for the dedicated cleaning and disinfection of shared medical equipment on each ward. The primary outcome is to demonstrate the effectiveness of improving the quality and frequency of cleaning shared medical equipment in reducing HAIs, as measured by a HAI point prevalence study (PPS). The secondary outcomes include the thoroughness of equipment cleaning assessed using fluorescent marker technology and the cost-effectiveness of the intervention. <h3>Discussion</h3></p> <p>Evidence from the CLEEN study will contribute to future policy and practice guidelines about the cleaning and disinfection of shared medical equipment. It will be used by healthcare leaders and clinicians to inform decision-making and implementation of best-practice infection prevention strategies to reduce HAIs in healthcare facilities. <h3>Trial registration</h3></p> <p>Australia New Zealand Clinical Trial Registry ACTRN12622001143718.</p>
dc.description.versionBefore publication
dc.identifier.citation<p>Browne, K., White, N., Tehan, P., Russo, P. L., Amin, M., Stewardson, A. J., Cheng, A. C., Graham, K., O'Kane, G., King, J., Kiernan, M., Brain, D., & Mitchell, B. G. (2023)<em>.</em> A randomised controlled trial investigating the effect of improving the cleaning and disinfection of shared medical equipment on healthcare-associated infections: the CLEaning and Enhanced disiNfection (CLEEN) study. <em>Trials, 24</em>(1), Article 133. https://doi.org/10.1186/s13063-023-07144-z</p>
dc.identifier.doihttps://doi.org/10.1186/s13063-023-07144-z
dc.identifier.issn1745-6215
dc.identifier.urihttps://research.avondale.edu.au/handle/123456789/34688453
dc.language.isoen_us
dc.rights<p>Used by permission: the author(s).</p>
dc.rights.licensehttp://creativecommons.org/licenses/by/4.0/
dc.subjectHospitals Cleaning Cross-infection Cost-effectiveness Shared medical equipment Infection control Health services Disinfection
dc.titleA Randomised Controlled Trial Investigating the Effect of Improving the Cleaning and Disinfection of Shared Medical Equipment on Healthcare-associated Infections: The CLEaning and Enhanced disiNfection (CLEEN) Study
dc.typeJournal Article
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